Potenza Prime
（Potenza PRIME）
The New Potenza Arrives
An advanced RF microneedle treatment device introduced by Cleo Beauty Clinic in Shinsaibashi, Osaka
A new treatment option for acne scars.
Introducing an upgraded Potenza
Simultaneous monopolar × bipolar irradiation. Condition-specific tips. Multi-layer needle design.
Potenza Prime keeps the strengths of the conventional model and has evolved to further improve treatment performance.
Cleo Beauty Clinic, which has more than 1,000 Potenza cases,
studies day and night to make the most of treatment with Potenza Prime.
Potenza Prime
(Potenza PRIME) — What Is It?
Potenza Prime (Potenza PRIME) is the latest model of the RF (Radio Frequency) microneedle treatment device “Potenza.”
*Our treatment policy is built on daily practice, the 2026 Japanese Society of Aesthetic Dermatology meeting, and discussions with CEO Kang of the device manufacturer Jeisys.
Ultra-fine microneedles are inserted into the skin and RF (radio frequency) energy is delivered from the needle tips, using the wound-healing response to promote collagen and elastin production and tissue remodeling.
The conventional Potenza has been highly regarded as a treatment device with a wide range of indications, including acne scars, pores, redness, and melasma.
Potenza Prime inherits that basic concept and has been updated in the following ways, evolving into a design that allows treatment better suited to each condition.
02Boost mode to improve drug delivery efficiency
03Needle structure
04Tip design
05Target layer
At Cleo Beauty Clinic in Shinsaibashi, Osaka, we have introduced Potenza Prime in addition to the conventional Potenza, and provide tailor-made treatment according to each patient’s concerns and skin condition.
What Has Evolved in Potenza Prime
Potenza Prime is not simply a model with new tips added.
The treatment design itself — how RF energy is delivered and which layer it acts on — has been reviewed, and an irradiation concept that was not possible with the conventional model has been adopted.
Here we introduce representative technical advances in Potenza Prime.
① Monopolar and bipolar RF can now be delivered simultaneously
Potenza Prime newly adopts an RF system that can deliver monopolar RF and bipolar RF at the same time.
Monopolar RF delivers thermal energy toward deeper parts of the skin and is suited to reaching the deep dermis. Bipolar RF, on the other hand, delivers heat at a targeted depth, spreading thermal energy broadly from the skin surface to the middle layer and acting uniformly on shallower layers.
With the conventional Potenza, it was also possible to use monopolar and bipolar RF separately, but they had to be switched and delivered one after the other.
With Potenza Prime, both can be delivered at the same time, so RF energy is designed to be delivered continuously from shallow to deep layers. This has been recognized to improve RF delivery efficiency, enabling more efficient delivery of thermal energy for various conditions such as acne scars, redness, and melasma.
At our clinic, we have been combining monopolar and bipolar RF even with the conventional Potenza
Although Potenza Prime can deliver monopolar and bipolar RF simultaneously, at our clinic we have also been treating with the conventional Potenza by switching between and combining monopolar and bipolar RF to make use of the characteristics of each.
By combining the deep approach of monopolar RF and the surface approach of bipolar RF, we perform irradiation aimed at delivering thermal energy widely from the shallow to the deep layers of the skin.
This irradiation method is one of the know-how for Potenza treatment that our clinic has built up through treating acne scars, redness, and more. With Potenza Prime, that treatment concept has been realized as simultaneous irradiation through the evolution of the machine.
② The new Boost Mode improves drug delivery efficiency
Boost Mode is a function newly installed in POTENZA PRIME that supports drug delivery during drug infusion.
While the conventional Potenza delivered drugs with a single stroke only, Potenza Prime’s Boost Mode repeatedly inserts and withdraws the needles into the skin multiple times, greatly improving drug delivery efficiency.
This is a new function unique to POTENZA PRIME that the older Potenza did not have.
Improved drug delivery efficiency through Boost Mode
While keeping the drug delivery technology that draws the skin in with negative pressure to introduce drugs into the skin, delivery efficiency has been improved by puncturing with the needles multiple times.
③ The needle design has evolved, adding a new option for acne scar treatment
For PMP-25N, the tip for acne scar treatment, the needle design itself has been reviewed.
With the conventional CP-25, the needle surface had an insulating coating, and RF energy was released only from the needle tip. This structure has the advantage of delivering thermal energy in a concentrated way to the target tissue.
In contrast, the PMP-25N newly adopted in Prime uses non-insulated needles. Because RF energy is released from the whole needle, it is designed to transmit thermal energy over a wider area than before.
As a result, the range of thermal action formed within the dermis has widened, making acne scar treatment with a different approach from before possible.
PMP-25I (New)
Insulated needle
→ RF is delivered only from the needle tip
PMP-25N (New)
Non-Insulated needle
→ RF is delivered from the whole needle
On the other hand, because thermal energy acts over a wider area, downtime may be longer compared with insulated needles.
For this reason, PMP-25N is not used for every patient; a doctor draws up the treatment plan after comprehensively evaluating the severity of acne scars, skin condition, treatment history, and tolerance for downtime.
We believe it is important to use insulated and non-insulated needles appropriately.
What we can say is that with PMP-25N, a new treatment method that can transmit thermal energy over a wider area than before has been added, which is a major step forward in Potenza treatment.
We believe it may offer a new treatment option for cases where improvement had plateaued with previous Potenza treatment, or cases where further improvement is desired.
Comparison of Downtime: PMP-25I vs. PMP-25N
Before treatment
With makeup removed, Potenza Prime treatment is about to begin.
Immediately after treatment
The right side (as viewed) is immediately after treatment with the PMP-25N tip, and the left side with the PMP-25I tip. The PMP-25N side shows slightly stronger redness, but overall downtime is mild compared with treatments such as Dermapen.
4 days later
The redness has disappeared. No difference is seen between left and right.
④ Dedicated tips have been developed for each condition, enabling more purpose-specific treatment
With the conventional Potenza, the design centered on one tip handling multiple conditions.
With Potenza Prime, dedicated tips have been developed for each condition, allowing irradiation design suited to each symptom. This makes it possible to choose the most suitable tip and plan treatment according to each patient’s concerns and skin condition.
| Indicated conditions | Conventional Potenza | Potenza Prime |
|---|---|---|
| Acne scars, craters, drug delivery | CP-25 | PMP-25I / PMP-25N |
| Pores | S-25 | PMP-25N with Jvelook drug delivery |
| Redness | S-25 | RSC-N25 |
| Melasma | S-16 | MLS2516 |
| Melasma + redness | ― | VMLS-N49 |
| Hair regrowth | ― | HGW-X16 |
| Acne | A-15 | ACN |
| Sagging / firmness | DIA | DIA F |
In particular, RSC-N25 (a dedicated redness tip), VMLS-N49 (which addresses melasma and redness together), and HGW-X16 (dedicated to hair regrowth) are tips newly added in Prime. This allows more appropriate treatment choices for symptoms that were difficult to address before and for cases with multiple skin concerns.
⑤ The needle structure has evolved, enabling a multi-layered approach from the epidermis to the dermis
With Potenza Prime, needle design is optimized for each condition, allowing irradiation suited to each condition from shallower to deeper layers of the skin than before.
For example, MLS2516, the tip for melasma treatment, adopts a dual mechanism that acts on the epidermis and dermis at the same time.
The short needle (non-invasive electrode) acts on melanocytes in the epidermis and suppresses melanin production. The long needle, on the other hand, delivers RF energy to the dermis, aiming to address existing pigment and improve the dermal environment.
The conventional Potenza focused on the dermis, but Prime is designed to approach both the epidermis and dermis at the same time, evolving the treatment concept for melasma itself.
Next, the HGW tip for hair regrowth uses the X Tip with long and short needles, promoting hair growth with three-dimensional RF irradiation that takes hair follicle structure into account.
- Deep-reaching coverage: With a non-contact design of short needles (0.6 mm) and long needles (0.9 mm), thermal energy spreads up to 1.3 mm deeper than the actual insertion depth, approaching deep structures.
Tips Used by Condition
With Potenza Prime, we propose treatment suited to each person’s skin condition by using tips designed specifically for each condition.
PMP-25I / PMP-25N
For acne scars and craters. While keeping the drug delivery technology that introduces medication, insulated and non-insulated needles are used as appropriate to design the range of thermal action to suit the symptom.
RSC-N25
A newly designed tip dedicated to redness. It delivers thermal energy uniformly from the surface to the middle layer, targeting excessively proliferated capillaries.
MLS2516
A tip dedicated to melasma. Its dual structure of short and long needles approaches both the epidermis and dermis, aiming to improve melasma.
VMLS-N49
A newly designed tip for cases with both melasma and redness. It approaches both symptoms at the same time.
HGW-X16
A new tip developed specifically for hair regrowth. It is designed to address the scalp environment.
Case Studies
*The cases shown are results of treatment with the conventional Potenza.
Potenza Prime is an upper model developed on the basis of the conventional device, and our clinic has accumulated many treatment results with the conventional Potenza. Drawing on that experience, we also provide treatment suited to each patient with Potenza Prime.
Potenza Case 01/03
Prices, Risks & Side Effects
Prices, Risks & Side Effects
| Prices | Potenza drug delivery with McCoom, 2 sessions Premium Potenza drug delivery with McCoom, 3 sessions Total: ¥408,000 |
| Risks & Side Effects | Temporary redness, scabs, peeling, and occasionally bruising |
Comment from the Treating Nurse
Treating nurse:R.S
The patient was concerned about acne and acne scars across the skin.
The patient had had acne since adolescence and had been troubled by it for a long time.
The patient received Potenza 5 times, the last 3 of which were performed with Premium Potenza.
Overall, craters and redness have decreased significantly.
The patient also felt that the skin felt smoother.
Comment from the Doctor
Treating doctor: Director Sara Motomura
The patient had both craters and redness, and was a case for which Potenza drug delivery was indicated.
Switching to Premium Potenza partway through the treatment produced better results.
The craters gradually became shallower and less noticeable, and the redness also improved.
Even deep acne scars from the past can be expected to improve with appropriate Potenza treatment.
Qualifications / Memberships
Japanese Society of Aesthetic Dermatology
Medical Art Makeup Society
Skincare Meister and Cosmetic Meister, Japan Cosmetic Association
Botox Vista Certified Physician
Juvederm Vista Certified Physician
JPCA Personal Color Assistant Advisor
Potenza Case 02/03
Prices, Risks & Side Effects
Prices, Risks & Side Effects
| Prices | Premium Potenza drug delivery with McCoom, 2 sessions Total: ¥179,200 |
| Risks & Side Effects | Temporary redness, scabs, peeling, and occasionally bruising |
Comment from the Treating Nurse
Treating nurse:A.T
The patient came wanting to make a better first impression at work.
The patient received a men’s set course that included Potenza.
Later, the patient also received eyebrow art makeup, and the overall impression of the face improved.
Comment from the Doctor
Treating doctor: Director Sara Motomura
The patient had craters and enlarged pores, and was a case for which Potenza drug delivery was indicated.
Switching to Premium Potenza partway through the treatment produced better results.
Heat was applied firmly with Premium Potenza to adhered acne scars, leaving the skin smoother.
Pores also improved, and the uneven areas beside the nose, which tend to be noticeable, became less noticeable.
Qualifications / Memberships
Japanese Society of Aesthetic Dermatology
Medical Art Makeup Society
Skincare Meister and Cosmetic Meister, Japan Cosmetic Association
Botox Vista Certified Physician
Juvederm Vista Certified Physician
JPCA Personal Color Assistant Advisor
Potenza Case 03/03
Prices, Risks & Side Effects
Prices, Risks & Side Effects
| Prices | Potenza Korean-style drug delivery with McCoom, 1 session: ¥69,600 |
| Risks & Side Effects | Temporary redness, scabs, peeling, and occasionally bruising |
Comment from the Treating Nurse
Treating nurse:S.N
After consultation with the doctor, treatment was performed with the Korean-style Potenza in Norine’s style.
Improvement in redness and craters can be seen.
Comment from the Doctor
Treating doctor: Director Sara Motomura
Irradiation settings were set so that the craters the patient was concerned about could be addressed thoroughly.
Improvement can be seen in the craters and redness on the cheeks and temples.
Craters in particular are visually noticeable when accompanied by redness, and many patients are bothered by them.
Therefore, Korean-style Potenza, which can approach both redness and craters, is a useful treatment method.
Qualifications / Memberships
Japanese Society of Aesthetic Dermatology
Medical Art Makeup Society
Skincare Meister and Cosmetic Meister, Japan Cosmetic Association
Botox Vista Certified Physician
Juvederm Vista Certified Physician
JPCA Personal Color Assistant Advisor
Our Clinic’s Approach | Commitment to Treatment Quality
Technical supervision by “Norine,” who provides Potenza technical instruction nationwide
Even with the same device, treatment quality varies greatly depending on irradiation depth, output settings, tip selection, and irradiation method.
At our clinic, under the technical supervision of “Norine,” who provides Potenza technical instruction at medical institutions nationwide, we hold regular technical training and strive to improve our irradiation skills.
Exchange of Opinions with Jeisys CEO Kang
In 2026, our clinic held a direct exchange of opinions with CEO Kang of Jeisys, the developer of Potenza. We discussed the treatment potential of Potenza Prime, our treatment policy, and the clinical practice of acne scar treatment in Korea and Japan.
We agreed to continue holding case review meetings and incorporating the latest knowledge to research protocols that improve treatment results.
Continuous Treatment Management by a Dedicated Nurse
Potenza is not a treatment that is completed in a single session.
At our clinic, we use a dedicated-nurse system, and adjust irradiation depth and output settings after continuously evaluating the reaction and progress from the previous session.
By understanding changes in skin condition with each session and irradiating to suit each person, we strive to provide more appropriate treatment.
Treatment Planning Based on VISIA Skin Analysis
We perform VISIA skin analysis and objectively evaluate redness, pigmentation, pores, hidden spots, and more, and then propose tip selection and a treatment plan.
Potenza Prime Price List
Potenza Prime — Limited-Number Monitor Program, Now Recruiting
We are currently recruiting monitors in connection with the introduction of Prime.This is offered at a special price for a limited number of people, so please consider this opportunity.
Monitor Conditions
- Skin analyzer measurements before treatment and one month after are included
- To convey the progress of treatment and the atmosphere of our clinic, we may introduce case photos and scenes during treatment or counseling on our website, Instagram, etc.
- When publishing, we take care so that individuals cannot be identified, and photos may be published without retouching. Thank you for your understanding and cooperation in advance.
- Please note that depending on your skin condition, the monitor program may not be applicable.
- Monitor conditions may be only partially listed, so please confirm the details at your examination at the clinic.
Frequently Asked Questions (FAQ)
Q. Which is better suited to me, the conventional Potenza or Potenza Prime?
From the standpoint of mechanism of action, Potenza Prime is considered to have a higher treatment effect.
At our clinic, we propose an appropriate treatment plan based on each person’s skin condition and the skin they aim for.
If you would like to know the treatment that suits you, please come in for a free counseling session.
Q. How long does the treatment take?
It varies depending on the treatment content, treated area, and whether anesthesia is used, but as a guide it takes about 30–60 minutes. Please ask the doctor or staff for details.
Q. Is it painful?
Depending on the treatment, anesthetic cream is applied before treatment to reduce pain. After treatment, a hot feeling continues until the next day, and for some people it can last 3–4 days. Pain is felt differently by each person, so we proceed while checking how you feel during treatment.
Q. Is there downtime?
Redness appears after treatment, and in many cases it almost disappears within 1–2 days.
You can wear makeup from the next day. The degree of downtime varies depending on the tip used and the irradiation area, so we explain it in detail beforehand at counseling.
Q. Can I be treated with tanned skin?
Treatment is available regardless of skin color, but right after sun exposure the skin is hot, which may cause unexpected side effects. We recommend treatment after the tan has settled.
Doctor
Director Sara Motomura
- 6 years of experience in aesthetic dermatology
- 2023: Opened Cleo Beauty Clinic
- Currently: Director, Cleo Beauty Clinic
Qualifications
- Skincare Meister and Cosmetic Meister, Japan Cosmetic Association
- Botox Vista Certified Physician
- Juvederm Vista Certified Physician
- JPCA Personal Color Assistant Advisor
Memberships
- Japanese Society of Aesthetic Dermatology
- Medical Art Makeup Society
