
About the Treatment
Electroporation (Careciss) is a treatment that uses short electrical pulses to create temporary electrical “holes” in the cell membranes of the stratum corneum cells for seconds to minutes, and delivers high-concentration beauty ingredients during that time.
This allows molecules that cannot penetrate by simple application to reach deeper layers (the dermis), delivering beauty ingredients.
By choosing the agent to be delivered according to the treatment goal, it is a high-power device that enables treatment suited to the symptom.
It delivers active ingredients that do not easily penetrate with everyday skincare deep into the skin, aiming to improve skin concerns.
The “holes” formed by treatment close quickly, so there is almost no downtime such as pain or redness.

Expected Effects
- Spots
- Fine lines
- Pores
- Acne
- Dullness
- Lack of moisture,
anti-aging - After Potenza,
after Dermapen:
skin soothing
Prices

| Choose the area — face, neck, backs of both hands Choose 2 serums (vitamin C, ceramide, niacinamide, tranexamic acid) | |
| First session | ¥4,980 |
| Single session | ¥6,980 |
| 5-session course Recommended as a set with Potenza, Dermapen, or peeling |
¥27,800 (20%off) |
| Backs of hands to below the elbow (both arms) | |
| First session | ¥9,960 |
| Single session | ¥13,960 |
| 5-session course Recommended as a set with Potenza, Dermapen, or peeling |
¥55,600 (20%off) |
| PepView agentadd-on (price per area; hands-to-elbow uses 2 areas) | +¥4,980 |

| Choose the area — face, neck, backs of both hands Choose 2 serums (vitamin C, ceramide, niacinamide, tranexamic acid) | |
| First session | ¥4,980 |
| Single session | ¥6,980 |
| 5-session course Recommended as a set with Potenza, Dermapen, or peeling |
¥27,800 (20%off) |
| Backs of hands to below the elbow (both arms) Choose 2 serums (vitamin C, ceramide, niacinamide, tranexamic acid) | |
| First session | ¥9,960 |
| Single session | ¥13,960 |
| 5-session course Recommended as a set with Potenza, Dermapen, or peeling |
¥55,600 (20%off) |
| PepView agent add-on (price per area; hands-to-elbow uses 2 areas) | +¥4,980 |

Our3 Points of Electroporation
01. 20 Times the Effect of Iontophoresis
Electroporation and iontophoresis both use electricity to deliver active ingredients to the skin, but they differ greatly in the types and amounts of ingredients that can be delivered.
- Iontophoresis ionizes beauty ingredients to deliver them into the skin, so substances that cannot be ionized, such as hyaluronic acid, collagen, and other large molecules, cannot be delivered deep into the skin.
- Electroporation, on the other hand,Electroporation creates “gaps” between skin cells with electricity, so even large ingredients can be delivered deep.For this reason, compared with iontophoresis,it is as much as “about 20 times” more effective, and can deliver to the lower dermis.
A wider variety of ingredients can also be delivered, so treatment options are broader than with iontophoresis.

| Electroporation | Iontophoresis | |
| Skin layers reached | Epidermis to lower dermis | Epidermis |
| Deliverable ingredients | · Ingredients that cannot be ionized can also be delivered ·Large-molecule ingredients(hyaluronic acid, collagen, etc.) · Water-soluble and fat-soluble substances | · Ingredients that can be ionized · Small-molecule ingredients · Water-soluble substances |
| Penetration rate | 80~90% | 10~15% |
02. Choice of Agents
At our clinic, the beauty serum can be selected according to your skin concerns.
All are serums suited to electroporation, and by selecting according to your skin condition at the time,skin problems can be addressed efficiently.
Please see the next section for details.
03. Soothing Effect
There are other electroporation devices, butcryo technology that allows delivery while adjusting temperature from 45°C to −25°Cis combined in cryo-electroporation, which is our Careciss S.
By cooling to −25°C,the skin can be soothed after treatments such as Potenza, Dermapen, and Laser Facial, shortening downtime such as redness, swelling, and inflammation.

Equipment and Solutions Used
Careciss S
With electroporation, agents that used to penetrate through gaps in the stratum corneum now penetrate directly through the “holes,”so about 20 times the amount of iontophoresis can be delivered, and agents that were hard to penetrate because of large molecules can be introduced without needle injection.
There is no pain or downtime such as redness after treatment.
Also,cooling constricts blood vessels, so the delivered agents remain in the skin longer, allowing the effect to be further exerted.

Solutions Applied
The agent to be applied can be selected according to your skin concerns.
Tell us about your skin concerns at counseling, and our doctors and nurses will recommend solutions from which high effects can be expected.
- Tranexamic acid: spots, skin roughness, anti-inflammatory action
- Vitamin C: brightening, acne
- Ceramide: moisturizing, improving the skin barrier function, skin beautifying and brightening effects
- Niacinamide: suppressing melanin production, easing UV damage through antioxidant action, suppressing skin roughness

We also offer the high-performance serum “PepView“.
It is rich in concentrated beauty ingredients and has high anti-aging effects, and we recommend it for those seeking results. (Optional fee: +¥4,980)
- It contains 15 kinds of abundant growth factors and high-performance peptides (cell-activating substances) that prevent oxidation of the skin, increase collagen, bring skin recovery and powerful regenerative function, and nourish the skin.
- 【[EGF (Epidermal Growth Factor)]
- Promotes cell regeneration and the creation of new cells
- Helps prevent and reduce wrinkles and raises skin metabolism to guide skin toward a healthy state.
- [IGF (Insulin-like Growth Factor)]
- Promotes production of collagen, elastin, and hyaluronic acid
- Improves skin firmness and elasticity and refines skin texture.
- [FGF (Fibroblast Growth Factor)]
- Promotes production of collagen, elastin, and hyaluronic acid
- In addition to improving firmness and elasticity, it improves skin troubles such as acne.
- It also contains KGF (keratinocyte growth factor), PDGF (platelet-derived growth factor), NGF (nerve growth factor), and TGF (transforming growth factor).
- 【[EGF (Epidermal Growth Factor)]
- Argireline, known as “topical Botox,” relaxes muscle tension and helps soften expression lines.
- Through vitamin C derivatives and arbutin, it helps reduce melanin pigment and brighten skin tone.


Treatment Flow
Counseling
We ask about the areas you are concerned about, propose a treatment, and a doctor conducts an examination. We also explain the treatment method in detail.
Makeup Removal
If you are wearing makeup, it is thoroughly removed with cleanser.
Treatment
The agent is applied and delivered with Careciss.
For soothing after treatments such as Potenza, only the cooling mode is used.
After Treatment
After treatment, the beauty ingredients remain on the face, so we recommend going home as is.
Contraindications
- People who are or may be pregnant, people using a pacemaker, and people with metal or mechanical objects inside the body
Side Effects and Risks
- Very rarely, the skin may turn temporarily red after treatment, but in most cases it improves with time.
FAQ
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How long does treatment take?
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It depends on your skin condition, but takes about 10–20 minutes.
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Is it painful?
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In many cases the treatment is barely painful.
If you feel pain or tingling from the weak electric current, the output can be adjusted, so please tell your practitioner.
If you are sensitive to electrical stimulation,treatment can be performed with the output adjusted.
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Is there downtime?
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No. You can wear makeup right after treatment.
Redness, swelling, and itching may rarely occur, but these are temporary reactions.
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How long should I wait between treatments?
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Treatment can bereceived even daily.
Continuing maintenance with 1–2 treatments a monthhelps keep the skin in better condition.

Doctor
Director Sara Motomura
- 6 years of experience in aesthetic dermatology
- 2023: Opened Cleo Beauty Clinic
- Currently: Director, Cleo Beauty Clinic
Qualifications
- Skincare Meister and Cosmetic Meister, Japan Cosmetic Association
- Botox Vista Certified Physician
- Juvederm Vista Certified Physician
- JPCA Personal Color Assistant Advisor
Memberships
- Japanese Society of Aesthetic Dermatology
- Medical Art Makeup Society

